个人简介
暨南大学化学与材料学院教授/博导,副院长;人工器官及材料教育部工程研究中心主任,技术委员会副主任委员。美国Clemson University,Virginia Commonwealth University访问学者。长期从事生物材料和组织工程的研究,特别是在硬组织再生修复方面,开展了从分子机理、仿生合成到类组织构建的系统研究,主持了该方向4个国家自然科学基金项目,探讨了生物分子有序结构对生物矿化无机物的形成组装的调控作用,在相关SCI期刊发表论文50余篇,获省部科技进步奖两项,参与专著编写4本。
学习经历
1997年9月至2002年6月,四川大学,获生物医学工程博士学位;
1986年9月至1997年6月,武汉理工大学,硅酸盐工程,本科。
工作经历
2002年至今,暨南大学历任讲师,副教授,教授
2009年至2010年,美国Clemson University,访问学者
2014年至2015年,美国Virginia Commonwealth University,访问学者
1990年至1997年,中国工程物理研究院工程师
研究方向
生物材料与组织工程,无机非金属材料,复合材料
主要论文(近5年)
1. Hongbo Yu, Xiaomu Xu, Zheng Xie, Xiuhong Huang, Licheng Lin, Yanpeng Jiao,* and Hong Li*. High-Efficiency Near-Infrared Light Responsive Antibacterial System for Synergistic Ablation of Bacteria and Biofilm.ACS Applied Materials & Interfaces 2022, 14, 32, 36947-36956
2. Shuyun Zhang, Xueshi Luo, Chuang Guo, Ke Huang, Ding Shan,Lihua Li*, Changren Zhou, Hong Li*. Tissue engineered bone via templated hBMSCs mineralization and its application for bone repairing. Biomaterials Advances. 2022, 212937
3. Shimei Li , Zengzhen Chen , Longfei Tan *, Qiong Wu, Xiangling Ren,Changhui Fu , Meng Niu , Hong Li *, Xianwei Meng ,* MOF@COF nanocapsule for the enhanced microwave thermal-dynamic therapy and anti-angiogenesis of colorectal cancer. Biomaterials, 283(2022) 121472-121484
4. Hongbo Yu, Yi Wan, Guiyin Zhang, Xiuhong Huang, Lichen Lin, Changren Zhou, Yanpeng Jiao and Hong Li*. Blood compatibility evaluations of two-dimensional Ti3C2Tx nanosheets. Biomedical Materials, 2022,17(2):
5. Wu S , Cheng X , Xu X , et al. In vivo and in vitro evaluation of chitosan-modified bioactive glass paste for wound healing[J]. Journal of Materials Chemistry B, 2022, 10.598-606
6. Manman Sun, Ke Huang, Xueshi Luo, Hong Li*. Templated Three-Dimensional Engineered Bone Matrix as a Model for Breast Cancer Osteolytic Bone Metastasis Process. International Journal of Nanomedicine. 2021;16:8391-8403.
7. Xueshi Luo, Shuyun Zhang, Binghong Luo, Hong Li*. Engineering collagen fiber templates with oriented nanoarchitecture and concerns on osteoblast behaviors. International Journal of Biological Macromolecules. 2021;185:77-86.(2021年化学升级版1区)
8. Yanyi Li; Haobin Huang; Chongwei Ding; Xiaoping Zhou; Hong Li*. β-Cyclodextrin-based Metal-Organic Framework as a Carrier for Zero-order Drug Delivery. Materials Letters. 2021:129766.
9. Zhiqiang Huang, Zhenzhao Guo, Manman Sun, Shaomao Fang, Hong Li*. Reduced Graphene Oxide-coated Electrospun Fibre: Effect of Orientation, Coverage and Electrical Stimulation on Schwann Cells Behavior. Journal of Materials Chemistry B. 2021:9: 2656-65
10. Ping He, Yanyi Li, Zhiqiang Huang, Zhen-Zhao Guo, Binghong Luo, Chang-Ren Zhou, Hong Li. A multifunctional coaxial fiber membrane loaded with dual drugs for guided tissue regeneration. Journal of Biomaterials Applications. 2020;34:1041-51.
11. Zhenzhao Guo, Jiao Genlong, Zhiqiang Huang, Hong Li*, Yao Ge, Zhe Wu5, Pei Yu and Zhizhong Li. Synergetic effect of growth factor and topography on fibroblast proliferation. Biomedical Physics & Engineering Express, 18 Nov 2020, 6(6) 065036
12. Ru Zhong, Quan Zhong, Meijun Huo, Binglin Yang, Hong Li*. Preparation of biocompatible nano-ZnO/chitosan microspheres with multi-functions of antibacterial, UV-shielding and dye photodegradation. International Journal of Biological Macromolecules. 2020;146:939-45.
13. Shumin Pang, Manman Sun, Zhiqiang Huang, Yuan He, Xueshi Luo, Zhenzhao Guo, Hong Li*. Bioadaptive nanorod array topography of hydroxyapatite and TiO2 on Ti substrate to preosteoblast cell behaviors. Journal of Biomedical Materials Research Part A. 2019;107:2272-81.
14. Shumin Pang, Xia Li, Dongwei Wu, Hong Li*, Xiupeng Wang*. Tuning inflammation response via adjusting microstructure of hydroxyapatite and biomolecules modification. Colloids and Surfaces B: Biointerfaces. 2019;177:496-505.
15. Shumin Pang, Yuan He, Ru Zhong, Zhenzhao Guo, Ping He, Changren Zhou, Bo Xue, Xuejun Wen, Hong Li*. Multifunctional ZnO/TiO2 nanoarray composite coating with antibacterial activity, cytocompatibility and piezoelectricity. Ceramics International. 2019;45:12663-71.
16. Zhiqiang Huang, Zhenzhao Guo, Manman Sun, Shaomao Fang, Hong Li*. A study on graphene composites for peripheral nerve injury repair under electrical stimulation. RSC Advances. 2019;9:28627-35.
17. Yao Ge, Rui-peng Chen, Hong Li, Zhenzhao Guo. Fiber membrane with orthogonal aligned surface for guided tissue regeneration. Materials Letters. 2018;228:301-4.
18. Shumin Pang, Yuan He, Ping He, Xueshi Luo, Zhenzhao Guo, Hong Li*. Fabrication of two distinct hydroxyapatite coatings and their effects on MC3T3-E1 cell behavior. Colloids and Surfaces B: Biointerfaces. 2018;171:40-8.
19. Xueshi Luo, Zhenzhao Guo, Ping He, Tian Chen, Lihua Li, Shan Ding, Hong Li*. Study on structure, mechanical property and cell cytocompatibility of electrospun collagen nanofibers crosslinked by common agents. International Journal of Biological Macromolecules. 2018;113:476-86.
20. Ping He, Quan Zhong, Yao Ge, Zhenzhao Guo*, Jinhuan Tian, Yehui Zhou, Shan Ding, Hong Li, Changren Zhou. Dual drug loaded coaxial electrospun PLGA/PVP fiber for guided tissue regeneration under control of infection. Materials Science and Engineering: C. 2018;90:549-56.
21. Zhenzhao Guo, Shuai Wu, Hong Li*, Qiyan Li*, Gang Wu, Changren Zhou. In vitro evaluation of electrospun PLGA/PLLA/PDLLA blend fibers loaded with naringin for guided bone regeneration. Dental Materials Journal. 2018;37:317-24.
22. Zhenzhao Guo, Dongying Bo, Yuan He, Xueshi Luo, Hong Li*. Degradation properties of chitosan microspheres/poly(L-lactic acid) composite in vitro and in vivo. Carbohydrate Polymers. 2018;193:1-8.
承担课题
1. 国家自然科学基金,组织工程三维多级有序微纳结构骨微环境作为乳腺癌骨转移体外模型的研究,(31971286,2019/01-2023/12,73万,主持)
2.国家自然科学基金,成骨细胞在仿Osteoid结构上生物矿化及其调控机制研究,(31571008,2016/01-2019/12,64万,主持)
3.国家自然科学基金:基于分子识别的原位仿生矿化再生修复牙硬组织的模拟研究(2009~2011,30870612,主持)
4.国家自然科学基金: 有序化纳米胶原纤维复合骨性靶向分子的体内外生物矿化机理研究(2011~ 2013,33万元,31070852, 主持)
5.广东省科技计划项目:分层接触引导纳米牙周组织再生膜研制及应用研究(2014.9-2016.12, 10万元,2013B010403015,主持)
讲授课程
材料科学基础(省一流课程),无机非金属材料学,生物材料,材料结构与性能,生物矿化
荣誉与奖励
获教育部科技进步奖二等奖1项;获广东省科技进步二等奖1项;
获广东省高校教师创新大赛特等奖(2022,生物材料),全国高校教师创新大赛二等奖(2022,生物材料)
社会职务
中国生物材料学会仿生材料分会和生物陶瓷分会委员、中国生物医学工程学会生物材料分会委员及分会秘书,广东省本科材料类教学指导委员会副主任,广东省科技特派员等。